Lisa

• Lisa is a 42-year-old woman who was diagnosed with ADPKD 6 years ago.

• Lisa works as an IT manager for a large retail chain and has a 14-year-old son who is unscreened.

• Lisa was diagnosed with hypertension at age 34.

• Lisa began experiencing bloating, nausea, early satiety, and flank pain; her gynecologist noted hepatomegaly and kidney enlargement and referred her to a nephrologist.

• MRI revealed bilateral, numerous cysts on the kidneys and Gigot II polycystic liver disease (1). 

• After a period of monitoring only, Lisa changed her insurer and began care under an ADPKD expert.

• She began disease modifying therapy with tolvaptan in 2020.

 

Family History

• Lisa has no family history of ADPKD or end-stage kidney disease (ESKD) (2).

• Lisa’s parents have declined genetic testing

• Comorbidities

• Hypertension

• Inguinal hernia

• Polycystic liver disease

• Recurrent urinary tract infections

 

Current Medications

• Lisinopril 20 mg/d

• Cephalexin 500 mg for postcoital prophylaxis

• Cholecalciferol 5000 IU/d

• Atorvastatin 20 mg/d

• Multivitamin

• Tolvaptan 90 mg at waking, 30 mg 8 hours later

• Octreotide 40 mg IM every 28 days